Causality Challenge

Apply causality assessment principles to complex cases

Role: Drug Safety Physician

Context: You're reviewing cases that require medical assessment of causality. Each case has different evidence patterns that affect the causality determination.

Task: Assess the causality for each case using standard criteria.

Step 1 of 3

Case 1: The Clear Picture

case

A 45-year-old male started Dermaclear cream for psoriasis. Within 3 days, he developed a localized rash at the application site. He stopped using the cream and the rash resolved in 5 days. Two weeks later, he tried the cream again (didn't realize it was the cause), and the rash recurred within 2 days in the same location. He stopped again and it resolved.

What is the most appropriate causality assessment?